Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15517335 | 0.83 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL16956565 | 0.81 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL13954749 | 0.80 | TSHR (0.52) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL20342651 | 0.80 | CES2 (0.54) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL7982038 | 0.79 | MAOA (0.43) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL17737722 | 0.79 | LMNA (0.54) | MEN1KMT2AMAPTIDO1ALDH1A1 | |
| SCHEMBL75563 | 0.79 | MEN1 (0.51) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL26070186 | 0.79 | MEN1 (0.40) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5489690 | 0.78 | LMNA (0.57) | LMNA | |
| SCHEMBL19661710 | 0.77 | PRSS1 (0.42) | KMT2AMAPTSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509602-B9 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | SENHWA BIOSCIENCES INC (TW) | 2017-11-01 | — | — | EP | disclosed |
| EP-2509602-B1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | SENHWA BIOSCIENCES INC (TW) | 2017-01-25 | — | — | EP | disclosed |