Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.41 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | PLG | P00747 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421242 | 0.88 | F2 (0.56) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7981150 | 0.87 | F2 (0.56) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8026453 | 0.83 | CNR2 (0.38) | CNR2CNR1OPRM1BCHE | |
| SCHEMBL7977875 | 0.73 | CNR2 (0.46) | F2F10PLGCNR2CNR1 | |
| SCHEMBL7427026 | 0.71 | F2 (0.43) | F2F10PLGKDM4EALDH1A1 | |
| SCHEMBL7968222 | 0.71 | ALDH1A1 (0.38) | F2F10PLGKDM4EALDH1A1 | |
| SCHEMBL8029667 | 0.70 | ITK (0.43) | F2F10PLGKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8029674 | 0.70 | F2 (0.45) | F2F10PLGCNR2BCHE | |
| SCHEMBL7968268 | 0.70 | F2 (0.45) | F2F10PLGKDM4EALDH1A1 | |
| SCHEMBL7985234 | 0.69 | F2 (0.69) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |