Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 8/20 | 0.36 |
| ▸ | F10 | P00742 | 7/20 | 0.36 |
| ▸ | PLG | P00747 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | BRD1 | O95696 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413755 | 0.79 | PPARG (0.47) | ALDH1A1MAPTKDM4EBRD4 | |
| SCHEMBL7427026 | 0.78 | F2 (0.43) | ALDH1A1F2F10PLGKDM4E | |
| SCHEMBL7426210 | 0.75 | F2 (0.46) | CNR2F2F10PLGKDM4E | |
| SCHEMBL7981313 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTCNR2F2F10 | |
| Hydrochloric Acid SCHEMBL8028429 | 0.71 | F2 (0.47) | CNR2F2F10PLG | |
| SCHEMBL7982258 | 0.71 | F2 (0.41) | ALDH1A1MAPTCNR2F2F10 | |
| SCHEMBL7426354 | 0.70 | F2 (0.55) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL7978111 | 0.69 | F2 (0.44) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426925 | 0.68 | F2 (0.72) | ALDH1A1CNR2F2F10PLG | |
| SCHEMBL7981516 | 0.67 | BRPF1 (0.42) | ALDH1A1CNR2F2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |