Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776566 | 0.84 | DRD2 (0.67) | DRD2DRD3ALDH1A1GAAPOLB | |
| SCHEMBL5393686 | 0.83 | DRD3 (0.69) | DRD2DRD3ALDH1A1GAAPOLB | |
| SCHEMBL14432037 | 0.81 | LMNA (0.48) | DRD2DRD3ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5451922 | 0.81 | LMNA (0.48) | DRD2DRD3ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1581709 | 0.79 | CYP1B1 (0.59) | ALDH1A1GAAACHEADRB2ADRB1 | |
| SCHEMBL6957478 | 0.77 | ACHE (0.74) | ALDH1A1GAAACHEADRB2ADRB1 | |
| SCHEMBL31232750 | 0.75 | DRD2 (0.84) | DRD2DRD3ALDH1A1GAAPOLB | |
| SCHEMBL9733689 | 0.75 | DRD2 (0.84) | DRD2DRD3ALDH1A1GAAPOLB | |
| SCHEMBL8247166 | 0.75 | CYP1B1 (0.62) | DRD2ALDH1A1NPSR1ACHEOPRL1 | |
| SCHEMBL30657539 | 0.75 | CYP1B1 (0.62) | DRD2ALDH1A1NPSR1ACHEOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |