Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250881 | 0.93 | NPC1 (0.54) | RAB9ANPC1CASP3SENP7ALDH1A1 | |
| SCHEMBL7982438 | 0.87 | NPC1 (0.48) | RAB9ANPC1CASP3SENP7ALDH1A1 | |
| SCHEMBL7245897 | 0.80 | ALDH1A1 (0.65) | RAB9ANPC1CASP3SENP7ALDH1A1 | |
| SCHEMBL358863 | 0.80 | RAB9A (0.47) | RAB9ANPC1CASP3SENP7ALDH1A1 | |
| SCHEMBL4004898 | 0.76 | CYP3A4 (0.47) | RAB9AALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL29111395 | 0.74 | HSD17B1 (0.44) | HSD17B1HSD17B2 | |
| SCHEMBL2957169 | 0.74 | NPC1 (0.70) | RAB9ANPC1CASP3SENP7ALDH1A1 | |
| SCHEMBL30785680 | 0.74 | NPC1 (0.70) | RAB9ANPC1CASP3SENP7ALDH1A1 | |
| SCHEMBL28893467 | 0.73 | HTR7 (0.41) | RAB9ANPC1ALDH1A1TDP1HPGD | |
| SCHEMBL21603046 | 0.72 | MAPK1 (0.46) | RAB9ANPC1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077116-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-10-18 | — | — | WO | disclosed |