SCHEMBL7982372

SCHEMBL7982372

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCNC(=O)c1ccc(C(F)(F)F)cc1F

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 19/20 0.44
PPARA Q07869 15/20 0.43
PPARG P37231 8/20 0.42
RHOC P08134 1/20 0.39
RHOA P61586 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979434 0.91 RHOC (0.39) PPARDPPARAPPARGRHOCRHOA
SCHEMBL7979282 0.89 RHOC (0.42) PPARDPPARAPPARGRHOCRHOA
SCHEMBL7975945 0.88 POLB (0.38) RHOCRHOA
SCHEMBL7976273 0.88 RHOC (0.47) PPARDPPARAPPARGRHOCRHOA
SCHEMBL7975921 0.85 RHOC (0.44) PPARDPPARAPPARGRHOCRHOA
SCHEMBL7977745 0.85 SCN9A (0.47) PPARDPPARGRHOCRHOA
SCHEMBL7982370 0.84 MAPT (0.37) PPARDPPARAPPARG
SCHEMBL7979083 0.83 RHOC (0.44) PPARDRHOCRHOA
SCHEMBL7979244 0.82 GAA (0.38) PPARDPPARAPPARGRHOCRHOA
SCHEMBL7979538 0.82 SCN9A (0.44) PPARDPPARGRHOCRHOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed