SCHEMBL7975945

SCHEMBL7975945

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCNC(=O)c1ccc(Cl)cc1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
FOLH1 Q04609 1/20 0.38
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
RHOC P08134 1/20 0.37
RHOA P61586 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
GCG P01275 1/20 0.35
NPC1 O15118 4/20 0.35
RAB9A P51151 2/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965905 0.89 FOLH1 (0.40) POLBTHRBRECQLTDP1L3MBTL1
SCHEMBL7982372 0.88 PPARD (0.44) RHOCRHOA
SCHEMBL8063136 0.85 NPC1 (0.48) TDP1L3MBTL1RHOCRHOAKMT2A
SCHEMBL7975943 0.83 NPSR1 (0.35) POLBTDP1L3MBTL1LMNAMAPT
SCHEMBL7979223 0.82 NPC1 (0.45) TDP1L3MBTL1RHOCRHOAKMT2A
SCHEMBL7977813 0.82 FOLH1 (0.40) POLBTHRBRECQLTDP1L3MBTL1
SCHEMBL7965830 0.81 NPC1 (0.46) L3MBTL1LMNARHOCRHOAKMT2A
SCHEMBL7979434 0.81 RHOC (0.39) RHOCRHOANPC1RAB9A
SCHEMBL8062554 0.80 KMT2A (0.48) POLBTHRBRECQLTDP1L3MBTL1
SCHEMBL8060866 0.80 NPC1 (0.47) TDP1L3MBTL1RHOCRHOAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed