Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557909 | 0.70 | EPHX2 (0.56) | ALDH1A1KDM4ESMN1; SMN2RAB9AHPGD | |
| SCHEMBL17033019 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2RAB9AHPGD | |
| SCHEMBL22239400 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2RAB9AHPGD | |
| SCHEMBL19385829 | 0.64 | KMT2A (0.38) | ALDH1A1TSHRCYP2C19CHRM2OPRM1 | |
| SCHEMBL10881713 | 0.64 | CYP1A2 (0.40) | ALDH1A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL15977374 | 0.62 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDTSHRCYP2C19 | |
| SCHEMBL4751174 | 0.61 | EPHX2 (0.41) | ALDH1A1KDM4ESMN1; SMN2HPGDEPHX2 | |
| SCHEMBL11035277 | 0.61 | TSHR (0.43) | ALDH1A1TSHRCYP2C19CHRM2OPRM1 | |
| SCHEMBL24343596 | 0.60 | CASP3 (0.42) | ALDH1A1KDM4ESMN1; SMN2RAB9AHPGD | |
| SCHEMBL3826438 | 0.60 | EPHX2 (0.44) | ALDH1A1KDM4ESMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007351-A1 | PROCESS FOR THE PREPARATION OF MEMANTINE AND ITS SALTS AND INTERMEDIATE FOR USE THEREIN | CIPLA LIMITED (IN) | 2010-01-21 | — | — | WO | disclosed |