Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | DRD3 | P35462 | 8/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982483 | 1.00 | DRD2 (0.46) | DRD2DRD3P2RX7 | |
| SCHEMBL8195613 | 0.97 | DRD2 (0.50) | DRD2DRD3P2RX7 | |
| SCHEMBL8195616 | 0.97 | DRD2 (0.50) | DRD2DRD3P2RX7 | |
| SCHEMBL7982371 | 0.94 | CA1 (0.42) | DRD2DRD3P2RX7 | |
| SCHEMBL7982369 | 0.94 | CA1 (0.42) | DRD2DRD3P2RX7 | |
| SCHEMBL8187458 | 0.81 | DRD2 (0.46) | DRD2DRD3P2RX7 | |
| SCHEMBL8195618 | 0.78 | DRD2 (0.50) | DRD2DRD3P2RX7 | |
| SCHEMBL7979784 | 0.78 | MGLL (0.37) | — | |
| SCHEMBL7976349 | 0.77 | KCNA3 (0.42) | — | |
| SCHEMBL7976352 | 0.77 | KCNA3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |