Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976349 | 1.00 | KCNA3 (0.42) | KCNA3SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7982357 | 0.88 | BCHE (0.41) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7982359 | 0.88 | BCHE (0.41) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7979784 | 0.84 | MGLL (0.37) | SLC6A2SLC6A3 | |
| SCHEMBL8195700 | 0.82 | KCNA3 (0.42) | KCNA3SLC6A2SLC6A3 | |
| SCHEMBL7982371 | 0.82 | CA1 (0.42) | — | |
| SCHEMBL7982369 | 0.82 | CA1 (0.42) | — | |
| SCHEMBL7977969 | 0.82 | SLC6A2 (0.36) | SLC6A2SLC6A3 | |
| SCHEMBL7977968 | 0.82 | SLC6A2 (0.36) | SLC6A2SLC6A3 | |
| SCHEMBL7979656 | 0.77 | HTR1A (0.42) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | claimed |
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |