Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982369 | 1.00 | CA1 (0.42) | CA1CA2DRD2DRD3LMNA | |
| SCHEMBL7982482 | 0.94 | DRD2 (0.46) | DRD2DRD3P2RX7 | |
| SCHEMBL7982483 | 0.94 | DRD2 (0.46) | DRD2DRD3P2RX7 | |
| SCHEMBL8195613 | 0.93 | DRD2 (0.50) | DRD2DRD3P2RX7 | |
| SCHEMBL8195616 | 0.93 | DRD2 (0.50) | DRD2DRD3P2RX7 | |
| SCHEMBL7979784 | 0.83 | MGLL (0.37) | — | |
| SCHEMBL7976352 | 0.82 | KCNA3 (0.42) | — | |
| SCHEMBL7976349 | 0.82 | KCNA3 (0.42) | — | |
| SCHEMBL7982357 | 0.82 | BCHE (0.41) | DRD2DRD3LMNA | |
| SCHEMBL7982359 | 0.82 | BCHE (0.41) | DRD2DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |