Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26833107 | 0.98 | SIGMAR1 (0.54) | GNAI3GNAO1GNAI1SIGMAR1HRH2 | |
| SCHEMBL2762291 | 0.85 | SIGMAR1 (0.50) | GNAI3GNAO1GNAI1SIGMAR1HRH2 | |
| SCHEMBL7983151 | 0.83 | HRH2 (0.51) | GNAI3GNAO1GNAI1SIGMAR1HRH2 | |
| SCHEMBL29790173 | 0.82 | L3MBTL1 (0.55) | MAPTKMT2ACES2CES1HAO1 | |
| SCHEMBL1144527 | 0.82 | L3MBTL1 (0.47) | MAPTKMT2ACES2CES1HAO1 | |
| Hydrochloric Acid SCHEMBL5617485 | 0.81 | CHRM5 (0.39) | GNAI3GNAO1GNAI1SIGMAR1KMT2A | |
| SCHEMBL1666993 | 0.79 | HSD17B10 (0.47) | MAPTKMT2ANAAA | |
| SCHEMBL14198493 | 0.79 | HSD17B10 (0.47) | MAPTKMT2ANAAA | |
| SCHEMBL14198492 | 0.79 | HSD17B10 (0.47) | MAPTKMT2ANAAA | |
| SCHEMBL8524266 | 0.79 | HSD17B10 (0.47) | MAPTKMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |