Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 11/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 10/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 10/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27517098 | 0.85 | POLB (0.58) | SIGMAR1MAPTKMT2AALDH1A1POLB | |
| SCHEMBL26833107 | 0.84 | SIGMAR1 (0.54) | HRH2HRH1GNAO1GNAI3GNAI1 | |
| SCHEMBL7983147 | 0.83 | GNAI3 (0.54) | HRH2HRH1GNAO1GNAI3GNAI1 | |
| Myristic Acid SCHEMBL30516888 | 0.80 | GPR84 (0.55) | GNAO1GNAI3GNAI1MAPTKMT2A | |
| Dodecanoate SCHEMBL29051670 | 0.80 | GPR84 (0.55) | GNAO1GNAI3GNAI1MAPTKMT2A | |
| SCHEMBL7932306 | 0.79 | MAPT (0.44) | HRH2HRH1GNAO1GNAI3GNAI1 | |
| SCHEMBL8524267 | 0.79 | THRB (0.53) | MAPTKMT2AALDH1A1 | |
| Water SCHEMBL27813121 | 0.78 | THRB (0.52) | MAPTKMT2AALDH1A1 | |
| Dodecanoate SCHEMBL28577977 | 0.78 | GPR84 (0.52) | HRH2HRH1GNAO1GNAI3GNAI1 | |
| Myristic Acid SCHEMBL29051786 | 0.78 | GPR84 (0.52) | HRH2HRH1GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |