Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26833107 | 0.87 | SIGMAR1 (0.54) | SIGMAR1CHRM5CHRM3GNAI3GNAO1 | |
| SCHEMBL7983147 | 0.85 | GNAI3 (0.54) | SIGMAR1CHRM5CHRM3GNAI3GNAO1 | |
| SCHEMBL18197679 | 0.83 | CHRM5 (0.52) | SIGMAR1CHRM5CHRM3GNAI3GNAO1 | |
| SCHEMBL30733932 | 0.83 | CHRM5 (0.53) | SIGMAR1CHRM5CHRM3POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4961046 | 0.82 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL15169051 | 0.79 | ALDH1A1 (0.44) | POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27804851 | 0.78 | SIGMAR1 (0.45) | SIGMAR1CHRM5CHRM3GNAI3GNAO1 | |
| SCHEMBL29299788 | 0.78 | HSD17B10 (0.45) | MEN1KMT2A | |
| SCHEMBL14195858 | 0.78 | PAOX (0.44) | SIGMAR1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL27749822 | 0.77 | SIGMAR1 (0.44) | SIGMAR1CHRM5CHRM3GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | claimed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | disclosed |
| EP-2391601-A1 | SULFAMOYL- PHENYL-UREIDO BENZAMIDINE-DERIVATIVES AS ANTIMALARIAL AGENTS | 4SC AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086177-A1 | SULFAMOYL- PHENYL-UREIDO BENZAMIDINE-DERIVATIVES AS ANTIMALARIAL AGENTS | 4SC AG (DE) | 2010-08-05 | — | — | WO | disclosed |