Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721775 | 0.93 | KMT2A (0.40) | KMT2AMEN1CNR2RAB9ANPC1 | |
| SCHEMBL10952972 | 0.78 | KMT2A (0.51) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL21299964 | 0.75 | NAMPT (0.55) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| Benzoic Acid SCHEMBL2518954 | 0.74 | KMT2A (0.50) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL11445146 | 0.71 | FDPS (0.42) | KMT2AMEN1CNR2FDPS | |
| SCHEMBL5680237 | 0.71 | NOS1 (0.52) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16047247 | 0.71 | KMT2A (0.52) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL6397506 | 0.71 | KMT2A (0.42) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL693477 | 0.71 | FNTA (0.47) | KMT2AMEN1CNR2NPC1SMN1; SMN2 | |
| SCHEMBL3401058 | 0.71 | KMT2A (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |