Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789981 | 0.92 | ALPL (0.48) | ALPLSLC40A1LMNAPIK3CAMTOR | |
| SCHEMBL791102 | 0.90 | ALPL (0.52) | ALPLSLC40A1BRAFGLO1PIK3CA | |
| SCHEMBL29556249 | 0.90 | ALPL (0.52) | ALPLSLC40A1BRAFGLO1PIK3CA | |
| SCHEMBL15648486 | 0.86 | ALPL (0.42) | ALPLLMNAHIF1AKEAP1NFE2L2 | |
| SCHEMBL15649596 | 0.82 | ALPL (0.40) | ALPLLMNAHIF1AALDH1A1KMT2A | |
| SCHEMBL790824 | 0.81 | ALPL (0.56) | ALPLSLC40A1PIK3CAMTOR | |
| SCHEMBL29556839 | 0.81 | ALPL (0.56) | ALPLSLC40A1PIK3CAMTOR | |
| SCHEMBL28554047 | 0.80 | ALPL (0.51) | ALPLSLC40A1PIK3CAMTORNAMPT | |
| SCHEMBL798076 | 0.80 | ALPL (0.47) | ALPLPIK3CAMTOR | |
| SCHEMBL22447713 | 0.79 | PIK3CA (0.47) | ALPLPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |