Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7981947 | 0.99 | KDM1A (0.41) | KDM1ACCR3DRD2SLC6A4SLC6A3 | |
| SCHEMBL7982506 | 0.95 | HTR7 (0.41) | CCR3SLC6A3HTR7GSK3BACHE | |
| Hydrochloric Acid SCHEMBL7983327 | 0.94 | HTR7 (0.41) | CCR3SLC6A3HTR7GSK3BACHE | |
| SCHEMBL7989275 | 0.92 | CCR3 (0.47) | KDM1ACCR3LTA4HGRIN2B | |
| Hydrochloric Acid SCHEMBL7986155 | 0.91 | CCR3 (0.47) | KDM1ACCR3LTA4HGRIN2B | |
| SCHEMBL7982426 | 0.91 | LTA4H (0.47) | KDM1AGSK3BLTA4HHTR4GRIN2B | |
| SCHEMBL7981938 | 0.91 | CACNA1I (0.43) | HTR7GSK3BACHELTA4H | |
| Hydrochloric Acid SCHEMBL7971795 | 0.90 | LTA4H (0.47) | KDM1AGSK3BLTA4HHTR4GRIN2B | |
| SCHEMBL7986176 | 0.90 | KCNH2 (0.46) | CCR3LTA4H | |
| Hydrochloric Acid SCHEMBL7986131 | 0.90 | CACNA1I (0.42) | HTR7GSK3BACHELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |