Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983389 | 0.93 | LMNA (0.42) | MAPTLMNAMEN1ALDH1A1ESR1 | |
| SCHEMBL7987829 | 0.84 | MAOB (0.38) | MAPTLMNAMEN1ALDH1A1ESR1 | |
| SCHEMBL7988507 | 0.83 | MMP2 (0.41) | GSTP1MCL1MAPTABCB1FFAR1 | |
| SCHEMBL7984732 | 0.83 | MMP2 (0.41) | GSTP1MCL1MAPTABCB1FFAR1 | |
| SCHEMBL7984522 | 0.79 | MRGPRX4 (0.37) | GSTP1MCL1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7987626 | 0.78 | ACACB (0.35) | GSTP1MCL1MAPTABCB1FFAR1 | |
| SCHEMBL6932601 | 0.76 | CFTR (0.43) | MCL1MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL7991411 | 0.76 | MMP2 (0.42) | MAPTLMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6026464 | 0.71 | EGFR (0.43) | MAPTLMNAMEN1ALDH1A1ESR1 | |
| SCHEMBL6026268 | 0.69 | CFTR (0.39) | MCL1MAPTLMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |
| US-6136832-A | RACEMIC MIXTURES AND ENANTIOMORPHS | OXIS INTERNATIONAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-6005000-A | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor | OXIS INTERNATIONAL, INC. (US) | 1999-12-21 | — | — | US | disclosed |