Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988507 | 1.00 | MMP2 (0.41) | MMP2MMP13GSTP1CA9MCL1 | |
| SCHEMBL7991411 | 0.92 | MMP2 (0.42) | MMP2MMP13CA9MAOBRIPK1 | |
| SCHEMBL7983512 | 0.83 | GSTP1 (0.40) | MMP2MMP13GSTP1MCL1ABCB1 | |
| SCHEMBL7984522 | 0.80 | MRGPRX4 (0.37) | MMP2MMP13GSTP1MCL1MRGPRX4 | |
| SCHEMBL7987626 | 0.79 | ACACB (0.35) | MMP2MMP13GSTP1MCL1MRGPRX4 | |
| SCHEMBL6932927 | 0.77 | CHRNA1 (0.42) | MMP2MCL1MAPT | |
| SCHEMBL7984718 | 0.77 | CHRNA1 (0.42) | MMP2MCL1MAPT | |
| SCHEMBL7983353 | 0.77 | CHRNA1 (0.42) | MMP2MCL1MAPT | |
| SCHEMBL7983389 | 0.75 | LMNA (0.42) | MMP2MMP13CA9MAOBMAPT | |
| SCHEMBL7987829 | 0.70 | MAOB (0.38) | MMP2MMP13MAOBRIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |
| US-6136832-A | RACEMIC MIXTURES AND ENANTIOMORPHS | OXIS INTERNATIONAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-6005000-A | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor | OXIS INTERNATIONAL, INC. (US) | 1999-12-21 | — | — | US | disclosed |