Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987626 | 0.85 | ACACB (0.35) | MRGPRX4GSTP1MMP2MMP13RIPK1 | |
| SCHEMBL7984732 | 0.80 | MMP2 (0.41) | MRGPRX4GSTP1MMP2MMP13RIPK1 | |
| SCHEMBL7983512 | 0.79 | GSTP1 (0.40) | GSTP1MMP2MMP13CYP1A2CYP3A4 | |
| SCHEMBL7991411 | 0.71 | MMP2 (0.42) | MMP2MMP13CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7983389 | 0.71 | LMNA (0.42) | MMP2MMP13CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7987829 | 0.67 | MAOB (0.38) | MMP2MMP13CYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL6932161 | 0.64 | MMP2 (0.35) | MMP2MMP13CYP1A2CYP2C9CYP2C19 | |
| Bicarbonate SCHEMBL9638235 | 0.60 | FFAR1 (0.71) | GSTP1CYP1A2CYP2C19MCL1FFAR1 | |
| SCHEMBL23483029 | 0.59 | LMNA (0.69) | GSTP1CYP1A2CYP2C19SMN1; SMN2MCL1 | |
| SCHEMBL1096817 | 0.59 | LMNA (0.69) | GSTP1CYP1A2CYP2C19SMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |
| US-6136832-A | RACEMIC MIXTURES AND ENANTIOMORPHS | OXIS INTERNATIONAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-6005000-A | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor | OXIS INTERNATIONAL, INC. (US) | 1999-12-21 | — | — | US | disclosed |