Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984984 | 0.88 | HDAC1 (0.61) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL7984813 | 0.83 | HDAC1 (0.53) | HDAC1HDAC6RAB9ANPC1POLB | |
| SCHEMBL7973491 | 0.82 | FLT1 (0.56) | HDAC1HDAC3HDAC2NPC1MAPT | |
| SCHEMBL7973227 | 0.82 | HDAC3 (0.53) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL7973254 | 0.82 | PLK1 (0.56) | RAB9ANPC1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7987817 | 0.82 | HTR7 (0.51) | HDAC1HDAC3HDAC2RAB9APOLB | |
| SCHEMBL7973501 | 0.81 | PTPN1 (0.53) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL7983702 | 0.79 | CA1 (0.57) | HDAC1HDAC3HDAC2RAB9ANPC1 | |
| SCHEMBL1355883 | 0.79 | PTPN1 (0.45) | HDAC8HDAC6CA1KMT2A | |
| SCHEMBL7984812 | 0.78 | PLK1 (0.59) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |