SCHEMBL7983702

SCHEMBL7983702

CCCS(=O)(=O)NC(=O)c1ccc(OC)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
PTGER4 P35408 1/20 0.53
PLK1 P53350 1/20 0.53
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
NPC1 O15118 4/20 0.50
RAB9A P51151 3/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GFER P55789 1/20 0.50
ALDH1A1 P00352 4/20 0.49
CYP1A2 P05177 2/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7983736 0.89 CA1 (0.62) CA1CA2TAS1R3TAS1R1PLK1
SCHEMBL7984812 0.86 PLK1 (0.59) TAS1R3TAS1R1PLK1NPC1RAB9A
SCHEMBL7987052 0.85 MMP1 (0.58) PLK1NPC1RAB9ATP53SMN1; SMN2
SCHEMBL7973370 0.82 TAS1R3 (0.58) TAS1R3TAS1R1NPC1RAB9ATP53
SCHEMBL7984813 0.82 HDAC1 (0.53) HDAC1NPC1RAB9ATP53SMN1; SMN2
SCHEMBL7973254 0.81 PLK1 (0.56) TAS1R3TAS1R1PLK1NPC1RAB9A
SCHEMBL7973227 0.81 HDAC3 (0.53) CA1CA2HDAC3HDAC1HDAC2
SCHEMBL7973491 0.81 FLT1 (0.56) CA1HDAC3HDAC1HDAC2NPC1
SCHEMBL7987817 0.81 HTR7 (0.51) HDAC3HDAC1HDAC2RAB9AALDH1A1
SCHEMBL7973501 0.80 PTPN1 (0.53) CA1HDAC3HDAC1HDAC2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed