Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990884 | 0.88 | OGG1 (0.55) | HDAC3HDAC1HDAC2POLBCTDSP1 | |
| SCHEMBL7984813 | 0.85 | HDAC1 (0.53) | HDAC1POLBHDAC6PTGS2PTPN1 | |
| SCHEMBL7973254 | 0.83 | PLK1 (0.56) | POLBPTPN1MAPTALDH1A1NPC1 | |
| SCHEMBL7973491 | 0.83 | FLT1 (0.56) | HDAC3HDAC1HDAC2POLBCTDSP1 | |
| SCHEMBL7987817 | 0.83 | HTR7 (0.51) | HDAC3HDAC1HDAC2POLBPTGS2 | |
| SCHEMBL7973501 | 0.83 | PTPN1 (0.53) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7989112 | 0.83 | L3MBTL1 (0.59) | POLBOGG1MAPTALDH1A1NPC1 | |
| SCHEMBL7983583 | 0.82 | HDAC1 (0.56) | HDAC3HDAC1HDAC2POLBHDAC11 | |
| SCHEMBL7983702 | 0.81 | CA1 (0.57) | HDAC3HDAC1HDAC2MAPTALDH1A1 | |
| SCHEMBL1355883 | 0.80 | PTPN1 (0.45) | HDAC8HDAC6PTPN1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |