Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990728 | 0.87 | HDAC1 (0.59) | HDAC1HDAC6ALDH1A1GAAL3MBTL1 | |
| SCHEMBL7973254 | 0.85 | PLK1 (0.56) | ALDH1A1GAAPTPN1NPC1RAB9A | |
| SCHEMBL7987817 | 0.85 | HTR7 (0.51) | HDAC1ALDH1A1GAAL3MBTL1PTGS2 | |
| SCHEMBL7973491 | 0.85 | FLT1 (0.56) | HDAC1ALDH1A1GAAL3MBTL1PTGS2 | |
| SCHEMBL7973227 | 0.85 | HDAC3 (0.53) | HDAC1HDAC6ALDH1A1PTGS2PTPN1 | |
| SCHEMBL7973501 | 0.84 | PTPN1 (0.53) | HDAC1HDAC6ALDH1A1GAAL3MBTL1 | |
| SCHEMBL7983583 | 0.83 | HDAC1 (0.56) | HDAC1HDAC6ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7983702 | 0.82 | CA1 (0.57) | HDAC1ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL1355883 | 0.81 | PTPN1 (0.45) | HDAC6PTPN1KDM1AKDM4EKMT2A | |
| SCHEMBL7987668 | 0.81 | HDAC8 (0.58) | HDAC6ALDH1A1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |