Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301451 | 1.00 | MTNR1A (0.43) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 | |
| SCHEMBL14301286 | 0.87 | MTNR1A (0.41) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 | |
| SCHEMBL14640070 | 0.85 | JAK1 (0.42) | PPARAPPARGMMP1 | |
| SCHEMBL12302732 | 0.84 | LDHA (0.53) | LDHAKMT2A | |
| SCHEMBL8222429 | 0.81 | KDM4E (0.42) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 | |
| SCHEMBL15219934 | 0.81 | KDM4E (0.42) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 | |
| SCHEMBL14301450 | 0.81 | PPARA (0.49) | PPARAPPARGITGB1ITGA4FFAR1 | |
| SCHEMBL7997577 | 0.79 | SRD5A2 (0.40) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 | |
| SCHEMBL14275445 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 | |
| SCHEMBL10064168 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BKDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048614-A2 | SHORT CHAIN PEPTIDOMIMETICS BASED ORALLY ACTIVE GLP-1 AGONIST AND GLUCAGON RECEPTOR ANTAGONIST | CADILA HEALTHCARE LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |
| WO-2009125424-A2 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LIMITED (IN) | 2009-10-15 | — | — | WO | disclosed |
| WO-2008062457-A2 | ANTIDIABETIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |