Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222429 | 1.00 | KDM4E (0.42) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12568311 | 0.87 | CYP1A2 (0.47) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8229997 | 0.87 | PPARG (0.50) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8229994 | 0.84 | JAK1 (0.46) | MMP1PPARGPPARA | |
| SCHEMBL12568308 | 0.83 | MMP1 (0.37) | MTNR1AMTNR1BMMP1MMP3CAPN1 | |
| SCHEMBL14942967 | 0.82 | LDHA (0.57) | MMP1MMP3SMN1; SMN2LDHAMMP2 | |
| SCHEMBL19545998 | 0.82 | LDHA (0.57) | MMP1MMP3SMN1; SMN2LDHAMMP2 | |
| SCHEMBL7983670 | 0.81 | MTNR1A (0.43) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14301451 | 0.81 | MTNR1A (0.43) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2000467 | 0.81 | TPH1 (0.54) | PPARGPPARASMN1; SMN2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084182-B1 | ANTIDIABETIC COMPOUNDS | CADILA HEALTHCARE LTD (IN) | 2013-08-28 | — | — | EP | disclosed |