Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301286 | 0.79 | MTNR1A (0.41) | SRD5A2MTNR1AMTNR1BFFAR1FFAR4 | |
| SCHEMBL14301451 | 0.79 | MTNR1A (0.43) | SRD5A2MTNR1AMTNR1BFFAR1FFAR4 | |
| SCHEMBL7983670 | 0.79 | MTNR1A (0.43) | SRD5A2MTNR1AMTNR1BFFAR1FFAR4 | |
| SCHEMBL10064167 | 0.78 | SRD5A2 (0.39) | SRD5A2MTNR1AMTNR1BFFAR1FFAR4 | |
| SCHEMBL25146375 | 0.77 | GAA (0.45) | SRD5A2PPARAPPARGSMN1; SMN2LDHA | |
| SCHEMBL14601306 | 0.76 | LDHA (0.49) | SRD5A2FFAR1FFAR4PPARAPPARG | |
| SCHEMBL30040624 | 0.75 | TPH1 (0.54) | PPARAPPARGSMN1; SMN2LDHA | |
| SCHEMBL2000467 | 0.75 | TPH1 (0.54) | PPARAPPARGSMN1; SMN2LDHA | |
| SCHEMBL429637 | 0.75 | TPH1 (0.54) | PPARAPPARGSMN1; SMN2LDHA | |
| SCHEMBL23512359 | 0.75 | KDM4E (0.49) | SRD5A2MTNR1AMTNR1BFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125424-A2 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LIMITED (IN) | 2009-10-15 | — | — | WO | disclosed |