Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984211 | 0.85 | STING1 (0.43) | STING1CYP3A4FGFR1L3MBTL1KDR | |
| SCHEMBL7994572 | 0.83 | NTRK1 (0.40) | STING1LMNATHRBL3MBTL1KMT2A | |
| SCHEMBL7994841 | 0.83 | LMNA (0.40) | STING1LMNATHRBKMT2AHSP90AA1 | |
| SCHEMBL7997825 | 0.81 | STING1 (0.47) | STING1FGFR1L3MBTL1KDR | |
| SCHEMBL7984304 | 0.80 | STING1 (0.49) | STING1FGFR1L3MBTL1KDR | |
| SCHEMBL7983874 | 0.80 | STING1 (0.43) | STING1LMNAL3MBTL1 | |
| SCHEMBL7983932 | 0.79 | STING1 (0.42) | STING1FGFR1L3MBTL1MEN1KMT2A | |
| SCHEMBL7983679 | 0.78 | HPGD (0.40) | STING1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL7995372 | 0.78 | STING1 (0.42) | STING1FGFR1L3MBTL1MEN1KMT2A | |
| SCHEMBL8001605 | 0.77 | LMNA (0.42) | EGFRLMNATHRBCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |