Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671298 | 0.88 | HSD11B1 (0.39) | HSD11B1CYP1A2 | |
| SCHEMBL7981154 | 0.87 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL7987597 | 0.84 | SLC22A12 (0.37) | HSD11B1 | |
| SCHEMBL12671327 | 0.83 | EGLN2 (0.36) | HSD11B1 | |
| SCHEMBL12677397 | 0.82 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL7985976 | 0.82 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL7993122 | 0.82 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL7981732 | 0.81 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL7970767 | 0.81 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL12677300 | 0.81 | MAPK14 (0.36) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |