Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7983445 | 0.81 | CHRM3 (0.37) | FPR3FPR2 | |
| SCHEMBL7981738 | 0.78 | KDM4E (0.55) | KDM4EPKMTGFBR1NAMPTACKR3 | |
| SCHEMBL7989480 | 0.74 | KDM4E (0.47) | KDM4EPKMTGFBR1NAMPTTP53 | |
| SCHEMBL7989477 | 0.74 | KDM4E (0.47) | KDM4EPKMTGFBR1NAMPTTP53 | |
| SCHEMBL7987167 | 0.72 | KDM4E (0.45) | KDM4EPKMNAMPTUSP30TP53 | |
| SCHEMBL8502163 | 0.72 | KDM4E (0.49) | KDM4EPKMFPR3FPR2TGFBR1 | |
| SCHEMBL8713112 | 0.72 | GPR119 (0.45) | KDM4EPKMTGFBR1 | |
| SCHEMBL7981945 | 0.71 | KDM4E (0.44) | KDM4EPKMNAMPTTP53 | |
| SCHEMBL13812320 | 0.70 | KDM4E (0.60) | KDM4EPKMFPR3FPR2KDM1A | |
| SCHEMBL31402457 | 0.70 | KDM4E (0.60) | KDM4EPKMFPR3FPR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |