Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863430 | 0.84 | GPR119 (0.46) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7863491 | 0.81 | GPR119 (0.45) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7863458 | 0.79 | FPR2 (0.43) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7871693 | 0.77 | GPR119 (0.43) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7863517 | 0.74 | GPR119 (0.46) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7868718 | 0.72 | PIK3CA (0.46) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7863410 | 0.72 | PIK3CA (0.46) | GPR119KDM4EPKMFAAH | |
| SCHEMBL7983977 | 0.72 | KDM4E (0.50) | KDM4EPKMTGFBR1 | |
| SCHEMBL948301 | 0.71 | GPR119 (0.48) | GPR119KDM4E | |
| SCHEMBL4518724 | 0.71 | GPR119 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |