Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989675 | 0.97 | SIGMAR1 (0.54) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL6644402 | 0.87 | PARP1 (0.49) | SIGMAR1HTR7PARP1PARP2 | |
| SCHEMBL7971720 | 0.85 | CCR3 (0.59) | SIGMAR1HTR7 | |
| SCHEMBL8557009 | 0.82 | CHEK1 (0.47) | SIGMAR1PARP1 | |
| SCHEMBL3174237 | 0.82 | CHEK1 (0.47) | SIGMAR1PARP1 | |
| SCHEMBL7986525 | 0.82 | CCR3 (0.56) | — | |
| SCHEMBL7983420 | 0.82 | HTR1A (0.55) | SIGMAR1HTR7 | |
| SCHEMBL7971599 | 0.81 | CCR3 (0.54) | SIGMAR1 | |
| SCHEMBL8554507 | 0.81 | SIGMAR1 (0.47) | SIGMAR1PARP1 | |
| SCHEMBL8667745 | 0.81 | WEE1 (0.40) | HTR7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |