Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971720 | 0.97 | CCR3 (0.59) | CCR3SIGMAR1HRH3SLC6A2SLC6A4 | |
| SCHEMBL7989675 | 0.84 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL27538872 | 0.84 | DRD2 (0.39) | CCR3SIGMAR1HRH3 | |
| SCHEMBL7986389 | 0.84 | CCR3 (0.50) | CCR3SIGMAR1 | |
| SCHEMBL24269416 | 0.82 | CHRM2 (0.40) | SIGMAR1 | |
| SCHEMBL7983983 | 0.81 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL7986525 | 0.81 | CCR3 (0.56) | CCR3 | |
| SCHEMBL7986154 | 0.80 | HTR1A (0.53) | SIGMAR1KCNH2 | |
| SCHEMBL27516853 | 0.79 | HTR1D (0.40) | — | |
| SCHEMBL6644402 | 0.77 | PARP1 (0.49) | SIGMAR1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |