Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286994 | 0.85 | ALDH1A1 (0.59) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL31170840 | 0.85 | ALDH1A1 (0.59) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL1694828 | 0.82 | MAPT (0.49) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL9558321 | 0.81 | POLB (0.46) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL231627 | 0.81 | MAPT (0.59) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL2710180 | 0.81 | MAPT (0.59) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL2742575 | 0.80 | MAPT (0.58) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL7564083 | 0.80 | POLB (0.52) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL7126615 | 0.80 | POLB (0.52) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL13520189 | 0.80 | POLB (0.52) | POLBMAPTNPSR1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |