Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998624 | 0.81 | KMT2A (0.35) | TP53ALDH1A1THRBKMT2ALMNA | |
| SCHEMBL7997710 | 0.80 | LMNA (0.48) | TP53ALDH1A1JAK2JAK1THRB | |
| SCHEMBL7994393 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7984361 | 0.79 | SMN1; SMN2 (0.36) | TP53ALDH1A1JAK2JAK1THRB | |
| SCHEMBL7984074 | 0.78 | TDP1 (0.38) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7994556 | 0.76 | HDAC1 (0.41) | ALDH1A1THRBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7994486 | 0.75 | HDAC6 (0.41) | TP53ALDH1A1THRBKMT2ALMNA | |
| SCHEMBL2022897 | 0.65 | POLB (0.53) | ALDH1A1KMT2ALMNA | |
| SCHEMBL27505254 | 0.65 | JAK2 (0.51) | TP53ALDH1A1JAK2JAK1HMOX1 | |
| SCHEMBL948318 | 0.65 | MAPT (0.59) | ALDH1A1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |