Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994393 | 0.82 | ALDH1A1 (0.42) | KMT2ALMNAPOLBGAATDP1 | |
| SCHEMBL7984074 | 0.81 | TDP1 (0.38) | KMT2APOLBTDP1SMN1; SMN2MAPT | |
| SCHEMBL7984367 | 0.81 | TP53 (0.38) | KMT2ALMNASMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7997629 | 0.78 | LMNA (0.47) | KMT2ALMNAPOLBGAASMN1; SMN2 | |
| SCHEMBL7994556 | 0.78 | HDAC1 (0.41) | KMT2ALMNASMN1; SMN2MAPTTHRB | |
| SCHEMBL7998619 | 0.77 | TP53 (0.35) | LMNAGAASMN1; SMN2THRBALDH1A1 | |
| SCHEMBL7994486 | 0.75 | HDAC6 (0.41) | KMT2ALMNASMN1; SMN2MAPTTHRB | |
| SCHEMBL2022897 | 0.65 | POLB (0.53) | KMT2ALMNAPOLBGAAMAPT | |
| SCHEMBL948318 | 0.64 | MAPT (0.59) | KMT2ALMNAPOLBGAASMN1; SMN2 | |
| SCHEMBL4688032 | 0.63 | ALDH1A1 (0.49) | LMNAPOLBTRPV1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |