Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994486 | 0.87 | HDAC6 (0.41) | HDAC1HDAC6SMN1; SMN2LTA4HTSHR | |
| SCHEMBL7997378 | 0.83 | LMNA (0.41) | HDAC1HDAC6FDPSSMN1; SMN2LTA4H | |
| SCHEMBL7994551 | 0.81 | HDAC1 (0.39) | HDAC1HDAC6FDPSSMN1; SMN2LTA4H | |
| SCHEMBL7998624 | 0.78 | KMT2A (0.35) | SMN1; SMN2KMT2ATHRBMAPTLMNA | |
| SCHEMBL7984367 | 0.76 | TP53 (0.38) | SMN1; SMN2KMT2ATHRBLMNAALDH1A1 | |
| SCHEMBL7994393 | 0.75 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7984074 | 0.74 | TDP1 (0.38) | SMN1; SMN2KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL7997738 | 0.69 | LMNA (0.41) | HDAC1HDAC6SMN1; SMN2LTA4HTSHR | |
| SCHEMBL7994472 | 0.68 | HDAC1 (0.39) | HDAC1HDAC6LTA4HKMT2AALDH1A1 | |
| SCHEMBL7997632 | 0.67 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRMAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |