Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | IL17A | Q16552 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991500 | 0.86 | ADORA2A (0.51) | KMT2AADORA2AADORA1ACHEADORA3 | |
| SCHEMBL7985633 | 0.86 | ADORA2A (0.54) | KMT2AADORA2AADORA1ACHEADORA3 | |
| SCHEMBL7984970 | 0.82 | PARN (0.43) | P2RX7PARNCNOT7 | |
| SCHEMBL7984891 | 0.78 | CNOT7 (0.50) | BRD4P2RX7ADORA2BPARNCNOT7 | |
| SCHEMBL7985328 | 0.78 | CNOT7 (0.51) | KMT2ABRD4P2RX7ADORA2BPARN | |
| SCHEMBL30054386 | 0.76 | BRD4 (0.54) | KMT2AMEN1ADORA2AADORA1BRD4 | |
| SCHEMBL348983 | 0.76 | BRD4 (0.54) | KMT2AMEN1ADORA2AADORA1BRD4 | |
| SCHEMBL7985287 | 0.75 | CNOT7 (0.40) | KMT2AMEN1ADORA2ABRD4ADORA3 | |
| SCHEMBL7975271 | 0.75 | CNOT7 (0.56) | KMT2ABRD4ADORA3ADORA2BPARN | |
| SCHEMBL7985350 | 0.75 | GAA (0.48) | P2RX7PARNCNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |