Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PARN | O95453 | 1/20 | 0.47 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974586 | 0.92 | GAA (0.52) | GAAPARNCNOT7P2RX7TP53 | |
| SCHEMBL7985228 | 0.90 | CXCR2 (0.50) | GAAPARNCNOT7P2RX7MAPT | |
| SCHEMBL7985707 | 0.88 | CYP11B2 (0.47) | GAAPARNCNOT7P2RX7MAPT | |
| SCHEMBL7974021 | 0.88 | TP53 (0.51) | GAAPARNCNOT7P2RX7TP53 | |
| SCHEMBL7985328 | 0.87 | CNOT7 (0.51) | PARNCNOT7P2RX7RXFP1HPGD | |
| SCHEMBL7985852 | 0.86 | TP53 (0.52) | GAATP53RXFP1MAPT | |
| SCHEMBL7988605 | 0.85 | GUSB (0.48) | PARNCNOT7P2RX7 | |
| SCHEMBL7975271 | 0.85 | CNOT7 (0.56) | PARNCNOT7RXFP1HPGD | |
| SCHEMBL7974409 | 0.85 | PARN (0.45) | GAAPARNCNOT7P2RX7TP53 | |
| SCHEMBL7991877 | 0.84 | P2RX7 (0.47) | GAAP2RX7L3MBTL1TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |