Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985633 | 0.91 | ADORA2A (0.54) | ADORA2AADORA1ADORA3ADORA2BACHE | |
| SCHEMBL7984414 | 0.86 | KMT2A (0.44) | ADORA2AADORA1ADORA3ADORA2BACHE | |
| SCHEMBL7987774 | 0.83 | CNOT7 (0.46) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7974480 | 0.81 | GUSB (0.50) | ADORA2BNPC1RAB9AKMT2A | |
| SCHEMBL7985228 | 0.80 | CXCR2 (0.50) | NPC1RAB9AKMT2A | |
| SCHEMBL7975271 | 0.80 | CNOT7 (0.56) | ADORA3ADORA2BKMT2A | |
| SCHEMBL7975135 | 0.78 | CNOT7 (0.52) | ADORA2AADORA2BNPC1RAB9AKMT2A | |
| SCHEMBL7984461 | 0.78 | CNOT7 (0.52) | ADORA2BKMT2A | |
| SCHEMBL7974508 | 0.77 | CNOT7 (0.51) | ADORA2BKMT2A | |
| Hydrochloric Acid SCHEMBL7985519 | 0.77 | CNOT7 (0.51) | ADORA2AADORA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |