Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985515 | 0.99 | ADORA2A (0.49) | ADORA2ASMN1; SMN2ALDH1A1ADORA3ADORA1 | |
| SCHEMBL7975267 | 0.92 | SMN1; SMN2 (0.46) | ADORA2ASMN1; SMN2ALDH1A1ADORA3ADORA1 | |
| SCHEMBL7988558 | 0.91 | SMN1; SMN2 (0.43) | ADORA2ASMN1; SMN2ALDH1A1ADORA3ADORA1 | |
| SCHEMBL7984459 | 0.90 | NR1H2 (0.43) | ADORA2ASMN1; SMN2ALDH1A1ADORA3ADORA1 | |
| SCHEMBL7974507 | 0.89 | MET (0.46) | ADORA2ASMN1; SMN2ALDH1A1ADORA3HPGD | |
| SCHEMBL7985060 | 0.88 | ADORA2A (0.39) | ADORA2ASMN1; SMN2HPGDMETCYP11B1 | |
| SCHEMBL7974441 | 0.88 | GRK2 (0.43) | ADORA2ASMN1; SMN2ALDH1A1ADORA3HPGD | |
| SCHEMBL7984490 | 0.87 | CNOT7 (0.41) | ADORA2AALDH1A1ADORA3ADORA1HPGD | |
| SCHEMBL7984659 | 0.87 | ALDH1A1 (0.44) | ADORA2ASMN1; SMN2ALDH1A1ADORA3ADORA1 | |
| SCHEMBL7985236 | 0.86 | LMNA (0.44) | ADORA2ASMN1; SMN2ALDH1A1ADORA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |