Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.36 |
| ▸ | GNRHR | P30968 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974542 | 0.89 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7984864 | 0.89 | ABCC8 (0.44) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7991397 | 0.88 | ABCC8 (0.43) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7985008 | 0.88 | ABCC8 (0.43) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7974275 | 0.87 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7992261 | 0.87 | TNKS (0.43) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7974486 | 0.86 | SMN1; SMN2 (0.50) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7984474 | 0.86 | ABCC8 (0.42) | ABCC8KCNJ11NR1H4GNRHRNR1I2 | |
| SCHEMBL7988015 | 0.86 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7985594 | 0.85 | GAA (0.48) | HPGDALDH1A1SMN1; SMN2ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |