Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984971 | 0.90 | ALDH1A1 (0.50) | HPGDALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7992261 | 0.90 | TNKS (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AABCC8 | |
| SCHEMBL7985008 | 0.89 | ABCC8 (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL7991397 | 0.89 | ABCC8 (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AABCC8 | |
| SCHEMBL7974275 | 0.88 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AABCC8 | |
| SCHEMBL7974486 | 0.87 | SMN1; SMN2 (0.50) | HPGDALDH1A1SMN1; SMN2KMT2AABCC8 | |
| SCHEMBL7984466 | 0.86 | HPGD (0.42) | HPGDALDH1A1SMN1; SMN2KMT2AABCC8 | |
| SCHEMBL7985594 | 0.86 | GAA (0.48) | HPGDALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7987948 | 0.85 | SMN1; SMN2 (0.50) | HPGDALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7988017 | 0.85 | KDM4E (0.43) | HPGDALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |