Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988488 | 0.86 | BRD4 (0.50) | HPGDPDE5AKMT2AMEN1ADORA2A | |
| SCHEMBL7984998 | 0.84 | PDE5A (0.52) | HPGDPDE5AKMT2AMEN1ADORA2A | |
| SCHEMBL7975265 | 0.82 | SMN1; SMN2 (0.61) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7988249 | 0.81 | PDE5A (0.50) | HPGDPDE5AKMT2AMEN1ADORA2A | |
| SCHEMBL7985373 | 0.81 | PDE5A (0.49) | HPGDPDE5AKMT2AMEN1ADORA2A | |
| SCHEMBL7974613 | 0.80 | CNOT7 (0.49) | HPGDPDE5AKMT2APOLBLMNA | |
| SCHEMBL7984499 | 0.80 | ADORA2A (0.43) | ADORA2ATLR7POLBPDE4DLMNA | |
| SCHEMBL7974064 | 0.80 | XDH (0.48) | HPGDPDE5AKMT2AMEN1ADORA2A | |
| SCHEMBL7984786 | 0.80 | SMN1; SMN2 (0.45) | HPGDPDE5AKMT2AMEN1POLB | |
| SCHEMBL7984716 | 0.80 | SMN1; SMN2 (0.53) | HPGDPDE5AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |