Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988495 | 0.86 | ADORA2B (0.46) | ADORA2APDE4DADORA2BPDE4APDE4B | |
| SCHEMBL7985002 | 0.84 | ADORA2B (0.48) | ADORA2APDE4DADORA2BPDE4APDE4B | |
| SCHEMBL7975271 | 0.82 | CNOT7 (0.56) | ADORA2BCNOT7ALDH1A1SMN1; SMN2PARN | |
| SCHEMBL7988254 | 0.81 | ADORA2B (0.50) | ADORA2APDE4DADORA2BPDE4APDE4B | |
| SCHEMBL7985382 | 0.81 | ADORA2B (0.46) | ADORA2AADORA2BCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7974620 | 0.80 | CNOT7 (0.58) | ADORA2ALMNAPOLBADORA2BCNOT7 | |
| SCHEMBL7984495 | 0.80 | HPGD (0.47) | ADORA2APDE4DTLR7LMNAPOLB | |
| SCHEMBL7984720 | 0.80 | CNOT7 (0.48) | LMNAADORA2BCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984791 | 0.80 | SMN1; SMN2 (0.45) | LMNAPOLBCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7974067 | 0.80 | ADORA2B (0.46) | ADORA2AADORA2BCNOT7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |