Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7987847 | 0.99 | OGA (0.40) | OGAHTTSMN1; SMN2CCR3DRD2 | |
| SCHEMBL7983767 | 0.91 | MEN1 (0.43) | OGAHTTSMN1; SMN2DRD2CHRM4 | |
| Hydrochloric Acid SCHEMBL7971699 | 0.90 | MEN1 (0.42) | OGAHTTSMN1; SMN2DRD2CHRM4 | |
| SCHEMBL7986651 | 0.85 | USP5 (0.38) | OGAHTTSMN1; SMN2DRD2ACKR3 | |
| SCHEMBL7982970 | 0.85 | ADRA1D (0.45) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7972919 | 0.84 | ADRA1D (0.44) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7971588 | 0.84 | USP5 (0.38) | OGAHTTSMN1; SMN2DRD2ACKR3 | |
| SCHEMBL7982974 | 0.84 | ADRA1D (0.42) | CCR3DRD2KMT2ADRD4DRD3 | |
| SCHEMBL7986596 | 0.84 | PRMT5 (0.43) | — | |
| SCHEMBL7982022 | 0.84 | DRD2 (0.36) | OGAHTTSMN1; SMN2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |