Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 4/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7983158 | 0.99 | DRD2 (0.36) | DRD2OGAHTTSMN1; SMN2NAPEPLD | |
| SCHEMBL7986067 | 0.90 | NAPEPLD (0.36) | NAPEPLDHTR4OPRL1 | |
| Hydrochloric Acid SCHEMBL7971952 | 0.89 | NAPEPLD (0.35) | NAPEPLDHTR4OPRL1 | |
| SCHEMBL7986050 | 0.85 | NPC1 (0.40) | OPRL1KCNH2CCR5 | |
| Hydrochloric Acid SCHEMBL7986635 | 0.84 | NPC1 (0.39) | OPRL1KCNH2CCR5 | |
| SCHEMBL7982970 | 0.84 | ADRA1D (0.45) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL7986651 | 0.84 | USP5 (0.38) | DRD2OGAHTTSMN1; SMN2HTR1A | |
| SCHEMBL7983124 | 0.84 | HDAC3 (0.51) | DRD2HTR4HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7972919 | 0.84 | ADRA1D (0.44) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL7984507 | 0.84 | OGA (0.40) | DRD2OGAHTTSMN1; SMN2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0954589-A1 | SYNTHETIC LEADER PEPTIDE SEQUENCES | NOVO NORDISK A/S (DK) | 1999-11-10 | — | — | EP | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998032867-A1 | SYNTHETIC LEADER PEPTIDE SEQUENCES | NOVO NORDISK A/S (DK) | 1998-07-30 | — | — | WO | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |