Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 9/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971588 | 0.99 | USP5 (0.38) | USP5DRD2DRD4DRD3OGA | |
| SCHEMBL7982970 | 0.86 | ADRA1D (0.45) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL7982974 | 0.85 | ADRA1D (0.42) | DRD2DRD4DRD3SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL7972919 | 0.85 | ADRA1D (0.44) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL7984507 | 0.85 | OGA (0.40) | USP5DRD2DRD4DRD3OGA | |
| SCHEMBL7986596 | 0.84 | PRMT5 (0.43) | — | |
| SCHEMBL7983767 | 0.84 | MEN1 (0.43) | DRD2DRD4OGAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7987847 | 0.84 | OGA (0.40) | USP5DRD2DRD4DRD3OGA | |
| SCHEMBL7982022 | 0.84 | DRD2 (0.36) | DRD2DRD3OGAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7987147 | 0.84 | ADRA1D (0.42) | DRD2DRD4DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |