Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 1.00 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | PRKACG | P22612 | 1/20 | 0.45 |
| ▸ | PRKACB | P22694 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983491 | 0.80 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7987250 | 0.78 | SRC (0.63) | SRCGABRA1GABRA5BRD4ALDH1A1 | |
| SCHEMBL19896290 | 0.77 | SRC (0.62) | SRCCNR2CHRNB2CHRNA4GUSB | |
| Hydrochloric Acid SCHEMBL19896459 | 0.76 | SRC (0.61) | SRCCNR2CHRNB2CHRNA4GUSB | |
| SCHEMBL3419641 | 0.72 | PKM (0.58) | SRCCHRNB2CHRNA4GABRA1GABRA5 | |
| SCHEMBL27175646 | 0.71 | CNR2 (0.61) | SRCCNR2GUSBGABRA1GABRA5 | |
| SCHEMBL19896388 | 0.71 | SRC (0.54) | SRCCNR2GUSBGABRA1GABRA5 | |
| SCHEMBL26966716 | 0.71 | SRC (0.54) | SRCCNR2GUSBFEN1 | |
| SCHEMBL9367302 | 0.69 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7962478 | 0.69 | SRC (0.52) | SRCCNR2CHRNB2CHRNA4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |