Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983209 | 0.83 | LCK (0.58) | FGFR1SRCLCKALDH1A1KDM4E | |
| SCHEMBL7983062 | 0.82 | LCK (0.50) | FGFR1LCKEGFR | |
| SCHEMBL7979955 | 0.82 | LCK (0.54) | FGFR1LCK | |
| SCHEMBL7969597 | 0.81 | PDE2A (0.46) | FGFR1LCKLMNAMAPTKMT2A | |
| SCHEMBL7983648 | 0.79 | LCK (0.57) | FGFR1SRCLCKALDH1A1KDM4E | |
| SCHEMBL7983558 | 0.79 | LCK (0.39) | FGFR1SRCLCK | |
| SCHEMBL7970474 | 0.78 | LCK (0.39) | FGFR1LCK | |
| SCHEMBL7983672 | 0.78 | FGFR1 (0.53) | FGFR1SRCLCKEGFR | |
| SCHEMBL7980189 | 0.78 | CAMK2D (0.44) | FGFR1LCKMEN1KMT2ANPC1 | |
| SCHEMBL7984553 | 0.78 | FGFR1 (0.49) | FGFR1SRCQPCTLCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |